A series of denials and a failure to formally investigate allegations of misconduct in Andrew Wakefields MMR research meant the public
was misled for six years about the credibility of the 1998 Lancet paper by Wakefield and colleagues.
Dr Fiona Godlee, BMJ Editor in Chief, says the UK has
consistently failed to take research misconduct seriously. She calls on the UK government to establish mandatory oversight
of clinical research integrity within the NHS, as happens for publicly funded
research in the USA.
In the third and final part of a special BMJ series,
Secrets of the MMR scare, investigative journalist Brian Deer reveals how the
medical establishment closed ranks to protect Wakefield after he raised concerns with the
Lancet in 2004.
Deers allegations included possible research fraud,
unethical treatment of vulnerable children, and Wakefields conflict of interest through his
involvement with a lawsuit against vaccine manufacturers.
Deer thought the editor, Richard Horton, would say that an
investigation was needed. Instead he reports that within 48 hours, and working
with the papers three senior authors, the journal was to publish 5000 words of
denials, in statements, unretracted to this day.
The statements said that an investigation was undertaken by
the Royal Free
Hospital that cleared Wakefield of wrongdoing.
But documents, emails, and replies obtained under the
Freedom of Information Act reveal no formal investigation. What emerges is
merely a scramble to discredit my claims during the 48 hours after I disclosed
the information, writes Deer. In short, the accused were investigating
themselves.