A new study has discovered that a problem in eye blinking conditioning (EBC) may aid in identifying children who have been exposed to alcohol while in the womb.
The discovery would identify children possibly affected by foetal alcohol syndrome (FAS) and also those who do not have distinctive FAS features.
The study led by Sandra W. Jacobson, a professor in the department of psychiatry and behavioural neurosciences at Wayne State University School of Medicine, also stated that all the children who have been exposed to alcohol show distinctive facial anomalies associated with FAS.
It was also mentioned in the study that while children with FAS have identifiable craniofacial abnormalities, children with alcohol-related neurodevelopmental disorder (ARND) may have considerable cognitive impairments without facial anomalies.
'Eyeblink conditioning (EBC) is a Pavlovian paradigm that involves temporal pairing of a conditioned stimulus, such as a tone, with an unconditioned stimulus, such as an air puff. Animal studies have shown that binge consumption of alcohol during pregnancy impairs EBC. We wanted to see if we could use the EBC paradigm to identify underlying or subcortical deficits that are specifically affected by prenatal alcohol exposure in children,' explained Jacobson.
'The present study provides the first documentation that clearly points to an FAS relationship because of the large sample size, the prospective follow-up of children from birth, and the careful measurement of prenatal exposure to alcohol and other drugs. Moreover, the deficits in EBC were not related to IQ or [found in nonexposed children with] microcephaly, which are often confounding factors,' said Lynn T. Singer, Deputy Provost and vice president for academic programs at Case Western Reserve University.