Is There a Connection Between Arthritis Pain Medication and Heart Attacks ?

by Savitha C Muppala on  September 15, 2010 at 8:34 PM Research News
RSS Email Print This Page Comment
Font : A-A+

Does the popular arthritis pain medication, Vioxx, cause heart attacks and strokes when taken in high doses ?
 Is There a Connection Between  Arthritis  Pain  Medication  and  Heart  Attacks ?
Is There a Connection Between Arthritis Pain Medication and Heart Attacks ?

The groundbreaking study, by a research team from the University of California, Davis and Peking University, China, may pave the way for a safer drug for millions of arthritis patients who suffer acute and chronic pain.

Using metabolomic profiling to analyze murine (rodent) plasma, the scientists discovered that Vioxx causes a dramatic increase in a regulatory lipid that could be a major contributor to the heart attacks and strokes associated with high levels of the drug and other selective COX-2 inhibitors, known as "coxibs."

"Our metabolomics study discovered that 20-hydroxyeicosatetrasanoic acid, also known as 20-HETE, contributes to the Vioxx-mediated cardiovascular events," said UC Davis bioanalytical chemist Jun-Yan Liu, the senior author of the paper and a five-year member of the Bruce Hammock laboratory.

The research will be published in the Proceedings of the National Academy of Sciences.

Source: ANI

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Drug Toxicity Osteoarthritis Oligoarthritis Spondylolisthesis Knee Replacement Heart Healthy Heart Reiterís syndrome Statins Mitral Valve Prolapse 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive