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Intravenous Aspirin Effective In Migraine Relief
Their study was published in the September 21, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.
The UCSF study participants were administered aspirin through an IV and 25 percent of the time they reported a significant reduction in pain three points on the 10-point pain scale. (A difference of three points downgrades a headache from severe to moderate, moderate to mild, or from mild to pain-free). Participants reported a more modest pain reduction about 40 percent of the time.
The findings are noteworthy because high-dose intravenous aspirin is not widely available for headache sufferers in the United States, the authors say. These results tell migraine sufferers, their doctors and insurance providers that high-dose intravenous aspirin is a beneficial way to treat difficult withdrawal headaches via a medicine that is not addictive or toxic, said Peter Goadsby, MD, PhD, lead investigator of the study, professor and director of the UCSF Headache Center. We hope to make this inexpensive therapy more available to patients seeking treatment for severe pain.
Many headache and migraine sufferers can manage pain without hospital stays. However, for severe pain that is difficult to manage, medication overuse often is a complicating factor. To develop a successful treatment plan for these patients, physicians first turn to a hospital inpatient program where medication withdrawal can be overseen by a neurologist or pain specialist. High-dose intravenous aspirin can help patients manage headache pain while undergoing medication withdrawal, the study shows.
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