Insomnia Cure Linked to Discovery of Eye Cells as ‘Brand New Target’: Study

by Thilaka Ravi on  August 19, 2008 at 3:38 PM Research News
  •   Print
  •   Share
  •   Comments
  •  Text 
A team of researchers at Oxford University has found hitherto unrecognized cells in the eye that could be a brand new target for the development of highly selective drugs to regulate sleep and wakefulness.

Most of us feel sleepy in a dimly lit place and alert in a bright place. The biological mechanism behind this was unexplained till now. The answer seems to be that specialized cells in the retina detect light and send brightness information to those regions of the brain that regulate sleep and levels of arousal.

The biological mechanism was discovered when the research team worked on mice in which the cells had been genetically turned-off. Mice normally sleep when it is daylight and wake up in the dark. The researchers observed that those mice in which the light-sensitive cells were turned off stayed wide-awake even when the lights were on.

According to their study published in the journal Nature Neuroscience, the team has been able to track the sleep pathway to the brain, showing that the retinal ganglion cells directly activated two sleep-inducing centers there.

Professor Russell Foster, the lead researcher said, “By targeting the specific mechanism controlling the action of retinal ganglion cells, it may be possible in the future to develop sophisticated treatments to regulate the sleep-wake cycles.”

A multibillion-dollar sleeping pill market thrives on developing and selling a lot many drugs to regulate the sleep-wake cycles. But current medicines are not very efficient and sophisticated and the drugs have side effects.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
X

Medwonders Health Network

  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
Quiz on Eye
An interesting eye quiz to update your knowledge on the subject.
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
Insomnia
Complete Medindia Resources
News Categories:  
Senior Health Center

Research Related News

» Overgrowth of Bacteria in Gut Blamed For Irritable Bowel Syndrome » New Drug That Only Attacks Cancer Cells Developed
» Personality Traits Linked To Longevity in Centenarians » Lack of Vitamin D in Diet Raises Stroke Risk in Japanese-Americans
» Why Bovine TB Continues to Spread Demystified in New Research » Seaweed Pill May Help Treat Arthritis
» P. Aeruginosa Infection Leads to Worse Outcomes and Increased Hospitalizations in COPD Patients » Hormone Boosts Production of Molecules Which Fight Skin Infection
Read More >>