In Women Undergoing IVF, Anxiety, Stress Major Factors of Depression

by Kathy Jones on  November 12, 2010 at 9:44 PM Mental Health News
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Stress, pre-existing depression, and anxiety are more likely than hormone therapy to impact a woman's depression levels when undergoing in vitro fertilization (IVF), a new research from Tel Aviv University has shown.

According to Dr. Miki Bloch of Tel Aviv University's Sackler Faculty of Medicine and the Sourasky Medical Center in Tel Aviv, these factors may also affect IVF success rates - so diagnosis and treatment of this depression is very important.

Bloch's research clarifies the involvement of different hormonal states as triggers for depression during IVF, both for long- and short-term protocols.

In the long-term IVF protocol, explains Bloch, women receive injections, which block ovulation, resulting in a sharp decline in estrogen and progesterone levels. This state continues for a two-week period before the patient is injected with hormones to stimulate ovulation, at which point the eggs are harvested and fertilized before being replanted into the womb.

The short-term IVF protocol, on the other hand, does not include the initial two-week period of induction of a low hormonal state.

Some gynaecologists believe that depression is more likely when a woman undergoes long-term IVF therapy because of those first two weeks of hormonal repression. But Bloch's research has demonstrated that the difference between the two different procedures is negligible - depression and anxiety rates for women who undergo the long protocol and those who undergo the short are exactly the same.

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