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In Some Patients Lower Blood Pressure may Preserve Kidney Function
"This is not a panacea. We have a lot more to figure out. But our evidence suggests that we have a way to at least delay or possibly even prevent end-stage kidney disease in some patients," says Lawrence J. Appel, M.D., M.P.H., a professor of medicine at the Johns Hopkins University School of Medicine and the study's leader.
End-stage kidney disease is the point at which patients need to be on dialysis or receive a kidney transplant in order to survive.
Still, not everyone in the study was helped by the aggressive blood pressure treatment. Those patients who had little or no protein in their urine — that is, patients who were not as sick — saw their kidney disease progress at roughly the same rate regardless of how low they tried to get their blood pressure. It was the sicker patients, that is, those with protein in their urine, who benefited most from the more intensive blood pressure therapy, with roughly a 25 percent reduction in end-stage kidney disease as compared with those who met the standard blood pressure goal. Roughly one-third of the participants had higher amounts of protein in their urine.
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