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Improved Endometrial Disease Diagnosis Possible With Ultrasound-guided Biopsy
Doctors use the SIS procedure to inject saline through a catheter threaded into the uterus through the cervix to fill up and expand the endometrial cavity. This makes it easy for them to visualize and biopsy an existing growth under sono guidance, and send it to a pathologist for analysis.
For their study, the researchers obtained a total of 88 saline-infusion sonography endometrial samples.
In the final outcome of 80 of those samples, saline-infusion endometrial sampling provided a diagnosis 89 percent of the time, compared with 52 percent for endometrial biopsy.
Dr. Moschos said that there were no women for whom blind biopsy of the endometrium would still be an appropriate first step. The blind biopsies missed 15 of 16 benign polyps and one-third of cancers.
By comparison, two-thirds of benign polyps were correctly diagnosed by saline-infusion sonography endometrial sampling and no premalignant or malignant growths were missed.
Dr. Moschos underscored the fact that abnormal bleeding is a common complaint among patients, particularly during and after menopause.
The researcher said that women experiencing such symptom need to be evaluated for any kind of gynecologic cancers, and that the first step should be imaging of the endometrium by ultrasound.
According to the American College of Obstetrics and Gynecology, postmenopausal women who have an endometrial lining thicker than 4 millimetres need further follow-up.
"In women with abnormal endometrial appearances, SIS should then be performed. If the endometrium is uniformly thickened on the SIS exam, only then is a blind biopsy appropriate. However, most endometrial pathology is focal, and therefore directed sampling, such as with saline infusion sonography guidance, is necessary," Dr. Moschos said.
The study has been published online in the journal Obstetrics and Gynecology.
Source-ANI
TAN
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More News on: Breast Biopsy, Endometrial Biopsy, Biopsy-Introduction, Prostate Biopsy, Biopsy-Specimen Processing, Skin Biopsy, Uterine Cancer
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