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Immune System Function Linked To Proper Food
Lynn Martin and co-authors conducted the study on deer mice and found that reduced food intake led to a decline in immune function in their subjects.
According to the researchers, the findings could have profound implications for human health.
Researchers have long remained puzzled by the question why immune activity is variable in many wild animals.
Referring to previous work on Peromyscus and other small mammals and birds, Martin said: "Animals live different lifestyles, so they may use different types of defenses against infection depending on the situation.
"Perhaps this is why immune defenses vary seasonally in most species; some may be too expensive to use all the time," Martin added.
It is already known that the immune system expends energy when it gears up to fight a virus or an infection.
In the study, the researchers found that restricting their subjects’ diet by 30 percent significantly decreased the amount of available B cells, which produce antibodies and maintain immune memory.
Without B cells, the immune system must relearn how to fight a threat if it reappears.
Martin and colleagues cite previous studies that have found that infections are ’more frequent and tend to be chronic in malnourished children.’
Vaccines, in order to work effectively, must provoke B cells to produce sufficient antibodies for immune memory.
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