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Ibuprofen Destroys Aspirin’s Potency in Preventing Stroke
The study, by researchers at the University at Buffalo, found that ibuprofen does so by undermining aspirin's ability to act as an anti-platelet agent.
As a part of the research, the boffins analysed 28 patients from the Dent Neurologic Institute who were taking both ibuprofen and aspirin daily.
On a first visit, the team led by Francis M. Gengo, Pharm.D, found that 13 patients had had a second stroke while taking aspirin and a NSAID, and that these patients had been platelet non-responsive to aspirin (aspirin resistant) at the time of that stroke.
When 18 of the 28 patients returned for a second neurological visit after discontinuing NSAID use, the researchers noted that they had regained their aspirin sensitivity and its ability to prevent blood platelets from aggregating and blocking arteries.
The study, the researchers say, is important as it is the first one of its kind to show the clinical consequences of the aspirin/NSAID interaction in patients being treated for prevention of a second stroke.
"This interaction between aspirin and ibuprofen or prescription NSAID's is one of the best-known, but well-kept secrets in stroke medicine," said Gengo.
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More News on: Bells Palsy, Diet Lifestyle and Heart Disease, Mitral Valve Stenosis And Mitral Valve Replacement, Congenital Heart Disease, Stress and the Gender Divide, Stroke Facts, Stroke, Geriatry-Related Diseases, Hyperventilation, Costochondritis
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