Scientists at Wake Forest University Baptist Medical
Center will be soon starting a human trail to asses if a cancer cure that
worked in mice will show the same results in humans as well.
The basic treatment includes transfusing white blood
cells, called granulocytes into patients having advanced cancer. A similar
treatment regimen in mice had worked successfully.
"In mice, we've been able to eradicate even highly
aggressive forms of malignancy with extremely large tumors," Zheng Cui,
Ph.D., lead researcher and associate professor of pathology said.
"Hopefully, we will see the same results in humans. Our laboratory studies
indicate that this cancer-fighting ability is even stronger in healthy
The researchers are seeking 500 healthy individuals to
donate white blood cells for the trial. Among them the 100 healthiest ones who
have the highest level of cancer-fighting activity in their WBCs will be chosen
to donate these cells.
between our study and the traditional white cell therapy is that we're
selecting the healthy donors based on the cancer-killing ability of their white
blood cells," said Cui. The participants will be monitored after three
months to asses if there are any clinical benefits from the therapy.