Scientists at UT Southwestern Medical Center have gained fresh insights into how the neurotransmitter dopamine, which is used by nerve cells to communicate with one another, helps brain cells to process important information.
Studying cells in mice, the researchers have found that this neurotransmitter causes certain brain cells to become more flexible, and changes brain-cell circuitry to process important information differently than mundane information.
"This can help one remember a new, important episode as distinct from any other episode, such as remembering where you parked your car today versus yesterday," said Dr. Robert Greene, professor of psychiatry at UT Southwestern.
"If we can one day manipulate the way that salient information is processed, we might be able to not only improve learning, but also improve the learning needed to extinguish severe fear responsiveness, such as when a soldier can't forget emotional war memories associated with post-traumatic stress disorder," he said.
Given that conditions like addictions and schizophrenia are associated with alterations in dopamine in the brain, the researchers believe that their findings may one day prove helpful in dealing with them.
It is known that dopamine is released in the brain in association with experiencing "important" events and remembering salient acts, such as learning to avoid a hot stove or that a good grade is rewarded.
Dr. Greene said that the current study focused on how dopamine operates on the cells associated with this type of memory formation.