How Much Fat You Burn May Be Regulated By Your Body Clock

by Tanya Thomas on  November 18, 2010 at 7:46 AM Diet & Nutrition News   - G J E 4
A new study could explain why people burn fat more efficiently at certain times of day.
How Much Fat You Burn May Be Regulated By Your Body Clock
How Much Fat You Burn May Be Regulated By Your Body Clock

UC Irvine researchers have discovered that circadian rhythms - the internal body clock - regulate fat metabolism. The find could lead to new pharmaceuticals for obesity, diabetes and energy-related illnesses.

Paolo Sassone-Corsi and his team found that a protein called PER2, which turns on and off PPAR-gamma's metabolic capabilities at regular intervals.

"What surprised us most, though, is that PER2 targets one specific amino acid on the surface of the PPAR-gamma molecule," Sassone-Corsi said.

"This kind of specificity is very rare in cell biology, which makes it exciting, because it presents us with a singular target for drug development."

Twenty-four-hour circadian rhythms regulate fundamental biological and physiological processes in almost all organisms. They anticipate environmental changes and adapt certain bodily functions to the appropriate time of day.

Disruption of these cycles can profoundly influence human health and has been linked to obesity, diabetes, insomnia, depression, heart disease and cancer.

The study appears this month in Cell Metabolism.

Source: ANI

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

View All