The weighted, combined data from 4 publications regarding VPT infants (n = 9,300) indicated that VPT infants born in lower-level hospitals have a 55 percent increase in odds of neonatal/predischarge mortality compared with those born in level III facilities (15 percent vs. 17 percent). Restricting to the 3 studies rated as adequate- and high-quality (n = 6,100 infants) reduced the estimate to a 42 percent increased odds of death (7 percent vs. 12 percent).
"The results of this review confirm a primary premise on which perinatal regionalization systems are based: high-risk infants have higher mortality rates when born outside hospitals with the most specialized levels of care. Although they represent less than 2 percent of U.S. births, 55 percent of infant deaths occur among VLBW infants. Strengthening perinatal regionalization systems in states with high percentages of VLBW and VPT infants born outside of level III centers could potentially save thousands of infant lives every year," the authors write.
"Future research should use appropriate risk adjustment and thorough reporting of hospital-level information. Further exploration of the effect of hospital volume, obstetrical level, infants that remain for care at lower-level hospitals after birth, and additional outcome measures such as long-term infant morbidity and fetal and maternal mortality will add to the understanding of this important intervention."
Source-Eurekalert