'Higher Breast Cancer Risk' for Thinner Girls

by Thilaka Ravi on  April 15, 2010 at 4:44 PM Cancer News
RSS Email Print This Page Comment
Font : A-A+

'Higher Breast Cancer Risk' for Thinner Girls
Researchers have observed that girls who are leaner at age seven are at higher risk of cancer later in life.

The finding has been published in BioMed Central's open access journal Breast Cancer Research.

Jingmei Li worked with a team of researchers from the Karolinska Institutet, Sweden, to study the relationships between childhood body size and tumour characteristics in a group of 2,818 Swedish breast cancer patients and 3,111 controls.

She said, "Our main finding was that a large body type at age seven years was associated with a decreased risk of postmenopausal breast cancer. Although strongly associated with other known risk factors such as age of menarche, adult BMI and breast density, size at age seven years remained a significant protective factor after adjustment for these other issues".

Size at age seven was also found to determine tumour characteristics, in particular, estrogen receptor status. A large body size at age seven was especially protective against estrogen receptor negative tumours, which generally fare worse in terms of prognosis. The researchers' classification of childhood body size was derived from nine numbered pictograms ranging from very skinny (S1) to very fat (S9). Subjects assessed their own body type at present and how they remembered themselves at seven years old. These selections were then used to group them as lean (S1 to S2), medium (S3 to S4) and large (S5 to S9).

Li said, "It appears counterintuitive that a large body size during childhood can reduce breast cancer risk, because a large birth weight and a high adult BMI have been shown to otherwise elevate breast cancer risk. There remain unanswered questions on mechanisms driving this protective effect".

Source: ANI
THK

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Women and Cancer Breast Biopsy Pagets disease of the breast Mastitis Cancer and Homeopathy Breast Cancer Facts Cancer Facts Cancer Tattoos A Body Art Breasts - Structures and Types 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive