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High Temperatures Reduce Contact Lens Solution's Anti-fungal Properties
When considering just the strains of Fusarium associated with the keratitis epidemic, ReNu with MoistureLoc that was stored at room temperature allowed fungal growth in 27 of 84 combinations, compared with 67 of 84 combinations for the bottle stored at 140 degrees Fahrenheit.
"The precise temperature, duration of exposure to elevated temperature and extent of temperature fluctuation that may diminish the antimicrobial activity of a particular contact lens solution is not known, and thus, additional studies may be warranted. However, our findings, coupled with the FDA reports of Bausch and Lomb’s failure to regulate the storage and transport temperatures of the products manufactured in their Greenville plant, may be significant," the authors wrote.
"Knowledge of the potential loss of antimicrobial activity of contact lens solutions and other pharmaceutical products when exposed to higher temperatures and the risk of such exposure when storing and transporting those products may help prevent such epidemics in the future," they added.
Source-ANI
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