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Hepatitis C Can Also Make You Vulnerable To Diabetes
A number of important investigators around the world have been arguing that fat in the liver is an extremely important determinant of insulin resistance, perhaps the most important. At least in this context, weve shown that not to be the case.
Before you get Type 2 diabetes, you must become insulin resistant and your insulin producing cells must also fail to compensate. Insulin resistance alone will not give you diabetes.
In our study, we gave intravenous glucose, a specific stimulus to insulin secretion, and showed that insulin secretion was not impaired in Hepatitis C patients compared to our control group.
This finding tells us that people with Hepatitis C who develop diabetes probably have susceptible insulin-producing cells, and would probably get it anyway but much later in life. The extra insulin resistance caused by Hepatitis C apparently brings on diabetes at 35 or 40, instead of 65 or 70.
More work now needs to be done into why Hepatitis C causes insulin resistance in muscle. That will give us better insight into the behaviour of the disease.
At this stage, it is helpful for people with Hepatitis C to understand insulin resistance and what it can mean for them. If they have relatives with Type 2 diabetes, they will be genetically prone to developing it themselves and so would be advised to manage their diets very carefully and take plenty of exercise to slow onset, Professor Chisholm
noted.
Source-Medindia
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More News on: Diabetic Retinopathy, Diabetes, Diabetic Diet, Hepatitis A, Hepatitis B, Diabetes - Essentials, Diabetes - Self-Monitoring of Blood Glucose (SMBG), Insulin Delivery Devices, Vasculitis , Diabetes and Exercise
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