A new treatment developed at Tel Aviv University uses laser-treated bone marrow stem cells to help restore heart function and health.
After a heart attack or stroke, heart scarring can lead to dangerously paper-thin heart walls and a decreased ability to pump blood through the body. Although the heart is unable to completely heal itself, this new treatment can help restore heart health.
Combining the therapeutic benefits of low-level lasers a process called "shining" and bone marrow stem cells, Prof. Uri Oron of the Department of Zoology at TAU's George S. Wise Faculty of Life Sciences has developed an effective, non-invasive procedure that significantly reduces heart scarring after an ischemic event, in which the heart is injured by a lack of blood supply. When the laser is applied to these cells a few hours after a heart attack, scarring can be reduced by up to 80 percent.
Prof. Oron's innovative method, which was recently reported in the journal Lasers in Surgery and Medicine, is ready for clinical trial.
Sending an SOS signal into the bone marrow
Though the heart is known to contain some stem cells, they have a very limited ability to repair damage caused by a heart attack, says Prof. Oron, and researchers have had to look elsewhere. One of the first efforts to use stem cells to reduce heart scarring involved harvesting them from the bone marrow and inserting them back into the heart muscle, close to the heart's blood supply, but this had limited success.