Hearing Loss Protected In Both Sexes By Female Sex Hormones

by Dr. Sunil Shroff on  March 4, 2008 at 7:21 PM Research News
RSS Email Print This Page Comment
Font : A-A+

Hearing Loss Protected In Both Sexes By Female Sex Hormones
A new study conducted on mice came out with an amazing finding that the female sex hormone, estradiol has the ability to protect hearing loss in both sexes.

Estradiol is present in both men and women, and is generated from testosterone in men by the protein aromatase.

The female sex hormone plays various roles in addition to its gender-specific ones, including having effects on the hearing (auditory) system.

In the new study, Barbara Canlon and colleagues at the Karolinska Institute in Stockholm, Sweden, investigated the role of estradiol-binding proteins, known as estrogen receptors, in response to auditory damage by examining hearing loss recovery in mice with deficiencies in various estrogen receptors.

The analyses found that mice deficient in only the estrogen receptor ER-beta had reduced recovery from auditory trauma, and that treatment with ER-beta-binding drugs protected mice from auditory damage.

Furthermore, not only was ER-beta found in the ears of both male and female mice, but levels of the nerve-protecting protein BDNF were reduced in mice that lacked either ER-beta or aromatase.

The authors concluded that this identification of an auditory-protective role for the estrogen receptor ER-beta may enable the development of new treatments for hearing loss.

The study is published in the Journal of Clinical Investigation.

Source: ANI
SUN/M

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Tinnitus Presbycusis Sex Facts Prostitution: Fresh Stakes in the Oldest Trade Sexual Intercourse Facts Acoustic Neuroma Safe Sex Top Ten Trivial Sex Facts Top Ten Sex Tips for Men Meniere’s Disease 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive