HPV Vaccine Against Anal Cancer Too

by Gopalan on  December 26, 2010 at 5:52 AM Cancer News   - G J E 4
The US FDA has expanded the approval of human papillomavirus (HPV) vaccine Gardasil for use against anal cancer too.

The vaccine may be used against anal cancer and pre-cancerous lesions in young people aged nine to 26 years old.
 HPV Vaccine Against Anal Cancer Too
HPV Vaccine Against Anal Cancer Too

Thus far the vaccine has been used to treat women with cervical, vulvar, and vaginal cancer, and associated lesions caused by HPV types 6, 11, 16, and 18.

"Treatment for anal cancer is challenging; the use of Gardasil as a method of prevention is important as it may result in fewer diagnoses and the subsequent surgery, radiation or chemotherapy that individuals need to endure," said Karen Midthun, director of the FDA Center for Biologics Evaluation and Research.

Although anal cancer is rare in the general population, its occurence is increasing especially among gay men, officials noted.

Human papillomavirus (HPV) is associated with about 90% of the estimated 5,300 cases of anal cancer diagnosed in the United States each year, the FDA said, citing statistics from the American Cancer Society. More women are diagnosed than men.

But Gardasil won't prevent development of anal precancerous lesions already present at the time of vaccination, the FDA said.

The most common adverse reactions to the vaccine include fainting, injection-site pain, headache, nausea and fever.

Source: Medindia

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