“Gut” Bacteria That Protects Against Type 1 Diabetes: Research

New research has brought to light a 'friendly' bacteria in the human gut that they say acts as a shield from Type 1 diabetes. The research was conducted at the Yale University and the University of Chicago.

In the study conducted using non-obese diabetic (NOD) mice, the researchers found that the common stomach bacteria influenced the overly robust immune system responses responsible for the disease.

Diabetic Diet - Diabetes Mellitus
The diabetic diet most often recommended is high in dietary fiber (especially soluble fiber) and nutrients, but low in fat (especially saturated fat) and moderate in calories.

Previous studies have already shown that NOD mice exposed to killed or non-active strains of tuberculosis or other disease-causing bacteria were protected against Type I diabetes, suggesting that the rapid "innate" immune response that normally protects from infections can significantly affect the onset of Type 1 diabetes.

The current study showed that the NOD mice deficient in innate immunity were protected from diabetes in normal conditions.

Lead researchers Li Wen, at Yale, and Alexander V. Chervonsky, at the University of Chicago, raised the mice in a germ-free environment, lacking "friendly'' gut bacteria.

Scientists Find the 'Real Culprit' Behind the Cause of Type 1 Diabetes
Scientists at Washington University School of Medicine in St. Louis have made a breakthrough in the fight against diabetes, by examining the immune cells long thought to be responsible

The results showed that mice lacking the 'good' bacteria found in human intestine developed severe diabetes.

"Understanding how gut bacteria work on the immune system to influence whether diabetes and other autoimmune diseases occurs is very important," Nature magazine quoted Li as saying.

Gut Bacteria may Play Key Role in Regulating Weight
The bacteria in the human gastrointestinal tract, known as gut microbiota, may play a key role in regulating weight, according to a new study.

"This understanding may allow us to design ways to target the immune system through altering the balance of friendly gut bacteria and protect against diabetes," Li added.

The study appears in journal Nature.

Type 1 Diabetes may Be the Outcome of Good Genes Behaving Badly
Researchers from Stanford University have revealed that type 1 diabetes may not be due to bad genes but rather to good genes behaving badly.

Source-ANI
TAN/M