Medindia

X

Growth of Fatal Skin Cancer Slowed Down

by Rathi Manohar on  July 11, 2010 at 12:07 PM Research News   - G J E 4
Melanoma, scientists at Queen's University have shown, can be slowed down in its deadly growth by a little known gene -MicroRNA.
Growth of Fatal Skin Cancer Slowed Down
Growth of Fatal Skin Cancer Slowed Down
Advertisement

Victor Tron, head of pathology and molecular medicine, focused on miR-193b when he discovered that it was deficient in melanoma tumors and because there were very few studies done about the gene.

Advertisement
The miRNA-193b gene is found in people's DNA and was unknown until 10 years ago.

"Our experiment was a bit of a fishing expedition in the beginning. We thought 193b might be important but the fact we got such a tremendous reaction - the melanoma really slowed down when we added 193b - was really startling," said Tron.

In experiments, increased levels of miR-193b increased in melanoma cells led to lower levels of a well-known protein called cyclin D1, and decreased melanoma cell growth.

Lab experiments with tissue samples proved that miR-193b plays a role in the melanoma process. Further studies will be needed to find out what causes miR-193b levels to go up and down.

"This is the first step in a long road towards finding a melanoma cure," said Tron.

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All