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Glaucoma Assessment and Treatment may be Improved by Findings from British Study
The study, published in the Investigative Ophthalmology & Visual Science journal (Intraocular Pressure and Corneal Biomechanics in an Adult British Population -- The EPIC-Norfolk Eye Study), reports the distribution and causes of eye pressure -- medically termed intraocular pressure (IOP).
According to the authors, researchers have long recognized that the clinical methods of assessing eye pressure have suffered from some inaccuracies, specifically as a consequence of the physical properties of the cornea. The EPIC-Norfolk study presents the first large-scale population-based measures of corneal biomechanics.
"Previously, a rather crude measure -- central corneal thickness -- was used as an index of corneal biomechanics," said author Paul J. Foster, MD, PhD, FRCS(Ed), of the University College London Institute of Ophthalmology, "We used a device which generates measures of corneal biomechanics in conjunction with IOP and attempts to 'correct' IOP for corneal physical properties."
Recruited between 1993 and 1997, the EPIC-Norfolk cohort was made up of approximately 25,000 predominantly Caucasian men and women aged 40 to 79 living in eastern England. From 2006 to 2010, a health examination was conducted to objectively assess various physical, cognitive and ocular characteristics of participants. The research team used a non-contact tonometer, the Ocular Response Analyzer, to obtain eye pressure and corneal biomechanical data from 4,184 study participants, now aged 48 to 91 years.
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