Medindia On Mobile
Custom Search

Register
Sign In
Sign In Using Facebook
HOME NEWS HEALTH A-Z HEALTH CENTRES HEALTH TOOLS DIRECTORIES SERVICES WEBSITES BUY ONLINE BLOGS COMMUNITY DOWNLOADS
Home » Research News

Genetic Switch to Limit Breast Cancer Chances Identified

by Gopalan on  May 28, 2009 at 9:53 PM Research News
  •   Print
  •   Share
  •   Comments
  •  Text 
Genetic Switch to Limit Breast Cancer Chances Identified
Scientists at the Medical Research Council Laboratory of Molecular Biology, UK claim to have identified the genetic switch that could help heal the crucial BRCA1 gene and limit chances of breast and ovarian cancers.


It is the gene’s inability to interact with CtlP, a protein, that could explain why BRCA1 remains unhealed, leading to breast and ovarian cancers.

By studying the interaction between BRCA1 and CtIP, the scientists discovered a switch that causes DNA breaks to be repaired using another identical piece of DNA as a template. Using the template makes sure the correct genetic sequence is restored without mistakes, thereby reducing the chance of introducing harmful mutations.

In a research paper appearing in Nature on 21 May, Dr Kevin Hiom and Dr Maximina H. Yun from the Cambridge laboratory describe how BRCA1 works.

Dr Hiom said: "Our findings help us to understand of how breaks in DNA strands can be repaired in a way that preserves our genetic code so that harmful mutations, which may lead to cancer, are kept to a minimum. We use chicken cells because they repair their DNA in a similar way to humans. Also we can easily create cells lacking different factors involved in DNA repair to study in the laboratory what happens when these factors are missing."

Cancer is caused by alterations in the sequence of the genetic material DNA. These mutations often arise when DNA becomes damaged, for example, through the generation of DNA breaks. Sometimes this damage is repaired accurately to restore the original DNA sequence and other times it is repaired inaccurately to produce a mutation.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
More News on: Women and Cancer, Breast Biopsy, Pagets disease of the breast, Mastitis, Breast Cancer Facts, Breasts - Structures and Types, Tattoos A Body Art, Breast Lumps, Breast Lumps-Screening, Breast Cancer
Comment & Contribute
Be the first to comment!
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions 		  

X

Medwonders Health Network

Total Members - 54994
Support Groups - 445
Login  Join Now
Medwonders Health Network
  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Oncology - Focus on Cancer Prevention
News Archive
Date :
Category :
Keyword :
Quiz on Cancer
Looking for information on cancer? Go through medindia's Cancer quiz.
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
Breast Cancer
Complete Medindia Resources
News Categories:  
Sexual Health Center

Research Related News
» Organ Damage in Inflammatory Genetic Disorder Arrested by Rheumatoid Arthritis Drug » Immune System Regulation Directly Affected If Raised on a Farm
» Shortly, Memory- Impaired Patients to Get Smartphone 'Prescription' » Sporting Activity in Excess Could Mar Long-Term Success of Hip Resurfacing
» Spread of Clostridium Difficile in Hospitals Probably Not by Contact With Infected Patients » Study Finds Cognitive Performance Decline After Natural Disasters
» Study Provides Evidence of Malaria's Impact on Fetal Growth » Research Sheds Light on Usefulness of Bubble-Propelled Microrockets
Read More >>
Follow us on : YouTube on Medindia.net Facebook on Medindia.net Twitter on Medindia.net Googleplus on Medindia.net Tumblr on Medindia.net RSS Iphone Digg on Medindia.net Stumbleupon on Medindia.net Delicious on Medindia.net

Consumers

Online Consults Child Health Teen Health Men's Health Women's Health Senior Health Sexual Health Mental Health Dental Health Kidney Health
Diabetes Obesity Vision Care Diet & Nutrition Know Your Body Amazing Body Facts Health Facts Conditions by Specialties Disease FAQs Medical Humour

Medical Professionals

Clinical Tools Health Videos Animation Slides Medical Aphorism Medical Conferences Jobs Journals Web Journals Open Access E-articles
Distance education Doctors Homepage Hospitals Homepage Personalize Info Matrimonial Print Oath Alumni Medical Humour Buy Books

Medical Students

Admissions Medical Colleges Medical Electives Medical Aphorism Post Grad Courses Indian Universities USMLE Centers CGFNS Centers
FRCS in UK PLAB USMLE CGFNS Alumni MCQ Bank Medical Humour Buy Books

Directories

Doctors Hospitals International Hospitals Chemists Surgical Suppliers NGOs Pharmaceuticals Medical Colleges
Home About us Career Sitemap Press Portfolio Advertise Contact Us
Disclaimer - The contents of this site are for informational purposes only. Always seek the advice of a qualified physician for any doubts.
Advertise with us Medindia Copyright Privacy Policy Terms of Use © All Rights Reserved 1997 - 2012