login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
Genetic Abnormalities In Pluripotent Stem Cell Lines
The published findings highlight the need for frequent genomic monitoring of pluripotent stem cells to assure their stability and clinical safety.
"We found that human pluripotent cells (hESCs and iPSCs) had higher frequencies of genomic aberrations than other cell types," said Louise Laurent, MD, PhD, assistant professor in the UCSD Department of Reproductive Medicine and first author on the study. "Most strikingly, we observed a higher frequency of genomic duplications in hESCs and deletions in iPSCs, when compared to non-pluripotent samples."
The ability of human pluripotent stem cells to become every cell type in the body has made them potential sources of differentiated cells for cell replacement therapies. "Since genetic aberrations are often associated with cancers, it is vital that cell lines destined for clinical use are free from cancer-associated genomic alterations," said senior author Jeanne F. Loring, PhD, professor and Director of the Center for Regenerative Medicine at the Scripps Research Institute.
|
|
|
More News on: Stem Cells - Cord Blood, Stem Cells - Fundamentals, Parkinsons Disease Surgical Treatment, Genetics and Stem Cells
 Comment & Contribute
|
- Health News Index
|
|
- News Quick Links
| News Categories: |
| » | Revision in Quality Standards for Heparin |
| » | Acne Drug Users At High Risk of Developing Eye Infections |
| » | Patients Who Take Antidepressants When in ICU More Likely to Die |
| » | New Tablet Coating Product by Ideal Cures, In Geneva |
| » | Prednisolone Benefits Patients With Bell's Palsy |
| More Drug News | |
|
