Genes Responsible for Being Generous

by Medindia Content Team on  December 9, 2007 at 12:00 PM Research News   - G J E 4
Genes Responsible for Being Generous
Researchers at the Hebrew University of Jerusalem have found that some people are genetically programmed to be generous.

The findings are based on an online task involving making a choice whether or not to give away money, the researchers found that those who chose to give away some or all of their money differed genetically from those involved in the exercise who chose not to give their money away.

For the study, the researchers conducted an experiment with 203 online 'players'. Each player could choose to keep the equivalent of 12 dollars he was allocated, or to give all or part of it to an anonymous other player. They also provided DNA samples, which were analysed and compared to their reactions.

It was found that those who had certain variants of a gene called AVPR1a gave on average nearly 50 percent more money than those not displaying that variant.

"The experiment provided the first evidence, to my knowledge, for a relationship between DNA variability and real human altruism," said Dr. Ariel Knafo, of the Psychology Department at the Hebrew University of Jerusalem.

The gene AVPR1a codes for the production of a receptor that enables a hormone, arginine vasopressin, to act on brain cells. Vasopressin, in turn, has been implicated in social bonding.

The researchers found greater altruism in players in which a key section of the AVPR1a gene, called its promoter, was longer. The promoter is the region of a gene that allows cellular machinery to bind to it and determine how much gene product is made. In the case of this gene, a longer promoter can result in greater activity.

According to the researchers, the findings could help biologists sort out altruism's evolutionary history. They noted that a version of AVPR1a also exists in rodents called voles, where it also promotes social bonding. This suggests that altruism has a long rooted genetic history, which may have taken on a new role during human evolution.

The results of the study were published online in the research journal Genes, Brain and Behaviour.

Source: ANI

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