Medindia

X

Genes Involved in Human Eye Color Identified

by Savitha C Muppala on  May 7, 2010 at 8:59 PM General Health News   - G J E 4
Boffins have zeroed in on three new genetic loci which are involved in the subtle differences of human eye colour.
 Genes Involved in Human Eye Color Identified
Genes Involved in Human Eye Color Identified
Advertisement

The study, led by Manfred Kayser of the Erasmus University Medical Center Rotterdam, The Netherlands, is published May 6 in the open-access journal PLoS Genetics.

Advertisement
Previous studies on the genetics of human eye colour used broadly-categorized trait information such as 'blue', 'green', and 'brown'; however, variation in eye colour exists in a continuous grading from the lightest blue to the darkest brown.

In this genome-wide association study, the eye colour of about 6000 Dutch Europeans from the Rotterdam Study was digitally quantified using high-resolution full-eye photographs. This quantitative approach, which is cost-effective, portable, and time efficient, revealed that human eye colour varies along more dimensions than are represented by the colour categories used previously.

The researchers identified three new loci significantly associated with quantitative eye colour. One of these, the LYST gene, was previously considered a pigmentation gene in mice and cattle, whereas the other two had no previous association with pigmentation.

These three genes, together with previously identified ones, explained over 50 percent of eye colour variance, representing the highest accuracy achieved so far in genomic prediction of complex and quantitative human traits.

"These findings are also of relevance for future forensic applications", said Kayser, "where appearance prediction from biological material found at crime scenes may provide investigative leads to trace unknown persons".

Source: ANI
SAV
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All