Gene Variations Linked to ADHD Identified

by Kathy Jones on  December 6, 2011 at 8:10 PM Genetics & Stem Cells News
RSS Email Print This Page Comment
Font : A-A+

Researchers at Children's Hospital of Philadelphia have identified genetic variations in the brain signaling pathways that may be linked to attention-deficit hyperactivity disorder (ADHD) leading to hope that new treatments could be designed in future to treat those who are affected by the variations.
 Gene Variations Linked to ADHD Identified
Gene Variations Linked to ADHD Identified

The researchers said that the mutations were in four genes of the glutamate receptor gene family and revealed that more than 10 percent of ADHD patients had this kind of variations. The researchers expressed hope that new drugs could be developed in future as part of treatment options for such patients.

The researchers conducted the study on 5,100 children, of which 1,000 of whom suffered from ADHD. They conducted complete genome analysis of all the children and compared the results with a larger group of nearly 12,000 children, 2,500 of whom had ADHD. They found variations in four genes among which gene GMR5 showed the strongest result.

"Members of the GMR gene family, along with genes they interact with, affect nerve transmission, the formation of neurons, and interconnections in the brain, so the fact that children with ADHD are more likely to have alterations in these genes reinforces previous evidence that the GMR pathway is important in ADHD", lead researcher Dr Hakon Hakonarson said.

Source: Medindia

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

DNA Finger Printing Dyslexia Attention Deficit Hyperactivity Disorder (ADHD) Bullying at School - Tips For Schools ADHD Dyscalculia / Learning Disabilities Diet to control Attention Deficit Hyperactivity Disorder 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive