A Swedish study has found a particular gene variant among people addicted to alcohol which puts them at increased risk of premature death.
Researchers at the Department of Psychology and the Sahlgrenska Academy at the University of Gothenburg, Sweden, have been investigating the dopamine D2 receptor gene and found that a variant of this gene is over represented in people with severe alcohol dependency.
They also found that that it is linked to a number of different negative consequences that can be of vital significance to the person affected.
"Our research shows that alcohol-dependent individuals, who are also carriers of this gene variant, run 10 times the risk of dying prematurely, compared with the average population," said Claudia Fahlke, a representative from the research team.
In a study the research team showed that this gene variant also appears to be associated with a higher tendency among these individuals to suffer a relapse, even if they have undergone treatment for their alcohol dependency.
This may provide one explanation as to the higher mortality rate in people suffering from alcohol dependency, who are carriers of this gene variant.
"This knowledge emphasises the importance of developing methods for early identifying individuals who are also carriers of this gene variant, since the consequences can be so serious," added Jan Balldin at the Sahlgrenska Academy, University of Gothenburg.
The study has been published recently in the journal Alcohol and Alcoholism (issue 46).