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Gene That Increases the Risk of Heart Attack, Heart Failure Identified
The findings are based on a study that revealed how a gene called osteoglycin (Ogn), which had not previously been linked with heart function, plays a significant role in regulating heart growth.
According to the study, the gene can behave abnormally in some people, and that this can cause the heart becoming abnormally enlarged.
The researchers hope that with a complete understanding of how enlarged hearts are linked to the workings of genes like Ogn, they will be able to develop new treatments for the condition, which affects a large proportion of those with high blood pressure, obesity and diabetes.
They hope that their findings will provide new avenues for treating people who either have an enlarged heart or are at risk of developing one, which can only be treated by lowering blood pressure currently.
In the study, researchers demonstrated that Ogn regulates the growth of the heart's main pumping chamber, its left ventricle.
If the left ventricle thickens, this creates a condition known as elevated Left Ventricular Mass (LVM), a major contributing factor for common heart diseases.
When the heart is enlarged it needs more oxygen and becomes stiff. This can cause shortness of breath or lead to a heart attack.
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More News on: DNA Finger Printing, Congenital Heart Disease, Stress and the Gender Divide, Heart Attack Facts, Heart, Heart Attack- Lifestyle Risks, Healthy Heart , Hyperventilation, Pulmonary Arterial Hypertension, Lifestyle Paths to Heart Disease
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