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Gender and Race Influence Immune Response to Dental Plaque

by Rajashri on  September 29, 2009 at 8:00 PM Dental News
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Recent research has indicated that brushing and keeping teeth free of plaque may do more than just beautify smiles. However consumers still have some doubts over the link between healthy teeth and a healthy body.

Will neglecting to brush your teeth damage more than just your smile? Can failing to attack dental plaque increase your risk of heart damage?
 Gender and Race Influence Immune Response to Dental Plaque


The answer to both questions may be yes if you are male and black, an Indiana University School of Dentistry study published in the current issue of the Journal of Dental Research reports.

The researchers, led by Michael Kowolik, B.D.S., Ph.D., professor of periodontics and associate dean for graduate education at the IU School of Dentistry on the campus of Indiana University-Purdue University Indianapolis, studied 128 black and white men and women and found that dental plaque accumulation did not result in a change in total white blood count, a known risk factor for adverse cardiac events. However, in black males the researchers noted a significant increase in the activity of neutrophils, the most common type of white blood cell and an essential part of the immune system.

Unlike most other studies that attempt to understand the link between oral inflammatory disease and heart disease risk, these study participants did not have periodontal disease. They were healthy individuals who by the study design were asked to neglect oral hygiene.

"We are talking about healthy people who simply neglect oral hygiene and if they were male and black, we found a response from their white blood cells, or neutrophils, that might be a cause for concern," said Dr. Kowolik.

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