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First Nations People on Peritoneal Dialysis Have Higher Risk of Infection and Death

by Kathy Jones on  July 27, 2010 at 10:01 PM General Health News
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A study published in CMAJ (Canadian Medical Association Journal has found that First Nations people in Canada on peritoneal dialysis are at increased risk of peritonitis and death, irrespective of whether they live in a rural or urban location.
First Nations People on Peritoneal Dialysis Have Higher Risk of Infection and Death


The high prevalence of diabetes, obesity and hypertension in Canada's First Nations, or aboriginal, population is fuelling the rapid growth of kidney disease and renal failure and consequent need for care and dialysis.

Peritonitis is inflammation of the peritoneum (the inner lining of the abdominal and pelvic walls), often caused by infection.

Peritoneal dialysis (PD) uses the peritoneum through which to filter wastes and excess water compared with hemodialysis which filters these externally through a filter. Hemodialysis requires living close to a dialysis centre whereas peritoneal dialysis can be conducted by patients at home. In Canada, approximately 18% of dialysis patients are on peritoneal dialysis.

The study, by researchers from St. Boniface General Hospital and the University of Manitoba in Winnipeg, Manitoba, looked at 727 adults with end stage renal disease on peritoneal dialysis from 1997 to 2007 in Manitoba. Of this total, 161 were First Nations and 566 non-First Nations.

"In this large cohort of peritoneal dialysis patients, First Nations status was associated with an increase in mortality and peritonitis after adjusting for baseline demographics, co-morbidities and peritoneal characteristics, and these findings were independent of residing in an urban or rural environment," writes Dr. Manish Sood with coauthors.

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