"Instead, NAFLD may be actively involved in the pathogenesis of CKD in type 2 diabetes, possibly through the release of some pathogenic factors from the liver," said Drs. Targher and Chonchol.Diabetes related kidney disease or diabetic nephropathy could lead to permanent loss of kidney function requiring dialysis or transplantation.
"The treatment of earlier stages of nephropathy in diabetes is effective in slowing the progression toward ESRD. Thus the early detection of precursors and risk factors of CKD is very important," the researchers added.
Researchers believe that intensive treatment might help in preventing or delaying development of CKD in these patients.
However, further study is needed to determine whether fatty liver is linked to an increased risk of CKD in patients without diabetes.
The study will appear in the August Journal of the American Society of Nephrology (JASN).
Source-ANI
RAS/L