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Fat in Body's Organs can Be Assessed by a Blood Test
Researchers from Harvard University and the University of Leipzig analysed 196 people, and found that genes that produce the protein RBP4 were up to 60 times more active in obese people with high levels of visceral fat than in lean people.
In contrast, the researchers found that the same genes were only 12 times more active in obese people with a preponderance of fat lying just under the skin.
The findings attain significance as the build-up of visceral fat has been linked to an increased risk of heart disease and type 2 diabetes.
According to the researchers, a treatment to cut levels of RBP4 may help provide health benefits. Previous studies had shown that reducing RBP4 levels in obese mice helped the animals to make better use of the hormone insulin, and thereby reduced their risk of diabetes.
It was also found that measures to improve insulin sensitivity in human subjects resulted in a reduction in the levels of the protein. "We believe that in the near future, measurements of RBP4 serum concentrations might serve as a novel biomarker for visceral obesity and increased risk for type 2 diabetes and other adverse outcomes of visceral obesity,” the BBC quoted researcher Dr Matthias Bluher as saying.
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