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Eye Infection from Adenoviruses can Be Treated by Gamma Globulin
August 30, 2007 at 5:00 PM
Research News
This treatment for pinkeye is very effectual and it could help prevent eye infections such as conjunctivitis. The results of the study is published in the September 1 issue of the journal Investigative Ophthalmology and Visual Science and is available online.
Conjunctivitis, commonly known as pinkeye, is an inflammation of the conjunctiva, the clear membrane that covers the white part of the eye and the inner surface of the eyelids. Although typically a mild, self-limiting disease in children and adults, newborns are particularly susceptible to pinkeye and can be more prone to serious health complications, even blindness, if it goes untreated. The most common cause of conjunctivitis is adenovirus infection.
Unfortunately, current treatments for conjunctivitis are not specifically targeted to the virus, and, presently, there is no FDA-approved therapy for the treatment of adenoviral-mediated eye infections.
In the study, led by Andrea Gambotto, M.D., assistant professor of surgery, University of Pittsburgh School of Medicine, the researchers investigated the antiviral activity of gamma globulin (Ig) on human “wild-type” adenovirus as well as adenovirus subtypes isolated from patients diagnosed with viral eye infections.
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