Expert Stress the Need for More Research on Scleroderma

by Sreeraman on  June 07, 2008 at 5:08 PM General Health News
  •   Print
  •   Share
  •   Comments
  •  Text 
Having a family member with scleroderma seems to increase a person’s risk for developing the disease, but other factors may be at play. “Familial studies suggest that there is an increased risk in first degree relatives of scleroderma patients,” Feghali-Bostwik said, but “our studies looking at concordance of scleroderma in twins suggest than an inherited genetic background is not sufficient to develop scleroderma.”

Some studies indicate that environmental factors may be involved in causing the disease. “Scleroderma is likely a multigenic disease with environmental components serving as triggers. These environmental factors possibly trigger scleroderma in individuals with a susceptible genetic background,” explains Feghali-Bostwik.

Scleroderma can be difficult to diagnose because the symptoms can mimic many other diseases, especially if the joints are involved. If scleroderma is suspected, a doctor often takes a thorough history. During the physical exam, the doctor will check for thickened or hardened areas on the skin.

Raynaud’s phenomenon, which is a disorder that affects the blood vessels in the fingers, toes, ear and nose, can be a sign of scleroderma. Doctors may order blood tests and/or take a tissue sample. People with scleroderma often have an elevation of certain antibodies and increased collagen production on skin biopsy.

There is currently no cure for scleroderma, but the symptoms can be managed with appropriate treatment. Topical treatments such as moisturizers and corticosteroids may help ease the skin symptoms. Medications such as anti-inflammatory drugs can ease joint stiffness and circulation problems can be addressed with calcium channel blockers and ACE inhibitors, which are most commonly used to treat high blood pressure. Other medications can help with digestive or pulmonary issues. More research is needed to shed light on this disease and hopefully make more progress toward a cure.

Source-Newswise
SRM
Previous Page 2 Page 1 | 2 
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
X

Medwonders Health Network

  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
Scleroderma
Complete Medindia Resources
News Categories:  
Senior Health Center

General News

» Ukraine Passes Law To Ban Smoking in Public Places » Eating 'Bushmeat' Could Lead to Next HIV Pandemic
» Reduction In Cost Of Anti Malarial Drugs Thanks To New Process » Younger People Who are Disagreeable Likelier to Prefer Aggressive Dogs
» Texas Photographer Creates Calendar With Pictures of Dogs in Yoga Positions » Polio Eradication at “Tipping Point,” Says WHO Chief
» Web-Based Decision Support System to Help People Select Right Wheelchairs » Study Says People Unaware About Dangers of Bee Pollen Supplements
Read More >>