Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
Exercise Induces Cell's Housekeeping Process | |
|
| |
 |  |  | Comments |  |
 |  |
 |
 |
 |  |
 |
 Text  |
Mouse study has offered initial proof that exercise stimulates autophagy, way by which a cell responds to starvation and other stresses by degrading broken or unwanted parts of itself to make energy.
It is sometimes called the cell's housekeeping pathway.
It is sometimes called the cell's housekeeping pathway.
This finding has led the UT Southwestern Medical Center researchers to suggest that the health benefits of exercise on blood sugar metabolism may come from the body's ability to devour itself.
"Exercise is known to have many health benefits but the mechanisms have been unclear. Autophagy is also known to have several health benefits, and these benefits correspond closely to the effects of exercise. We hypothesized that some of the health benefits of exercise might be explained through autophagy," said senior author Dr. Beth Levine, professor of internal medicine and microbiology who leads the Center for Autophagy Research at UT Southwestern.
Dr. Levine, a Howard Hughes Medical Institute (HHMI) investigator at the medical center, decided to focus on one specific health effect of exercise - the ability of exercise to prevent blood sugar abnormalities in the face of a high-fat diet.
The researchers found that mice genetically unable to increase autophagy in response to short-term exercise have decreased endurance and fail to experience the normal benefits of exercise on blood sugar metabolism.
This discovery led the team to investigate whether autophagy is important in the protective effects of chronic exercise on diabetes. A high-fat diet induced diabetes-like changes in blood sugar metabolism in both control mice and in test mice that were genetically unable to increase autophagy above baseline levels, said Dr. Congcong He, lead author and a postdoctoral researcher in Dr. Levine's lab.
However, the researchers found that exercise reversed these blood sugar abnormalities in control mice but not in the autophagy-deficient mice.
"Our finding that exercise fails to improve glucose metabolism in autophagy-deficient mice strongly suggests that autophagy is an important mechanism by which exercise protects against diabetes," said Dr. Levine.
"It also raises the possibility that activation of autophagy may contribute to other health benefits of exercise, including protection against cancer, neurodegenerative diseases and aging, Dr. Levine stated.
The finding was reported in the journal Nature.
Source-ANI
| |
|
|
More News on: Physiotherapy Utilities, Diet Lifestyle and Heart Disease, Tips to Live Longer, Exercise and Fitness, Lifestyle Modification: No Big Deal!, Body Types and Befitting Workouts, Exercise To Gain Weight, Top Health Tips to Overcome Tiredness, Fitness Through Density Training Program, Exercises to Grow Taller
 Comment & Contribute
|
Related Links
Exercise
It is important for us to understand the power of daily exercise. Only then can we motivate ourselves to inculcate the habit of exercise on a daily ...
Exercise and Fitness
Exercise is about revamping your lifestyle, not just weight loss. Exercise to get healthy - that way, you'll last longer at it and get better ...
Exercise Stress Test
A stress test is used to test for heart disease. Exercise stress test is also called exercise electrocardiogram, treadmill test, graded exercise ...
Resting Metabolic Rate
Understanding how metabolic process is regulated and what factors affect the same is crucial before adopting any fitness ...
Research Related News
Study Explores How Peer Pressure Drives Applause
If you see a play that you privately think is boring, will you keep silent when everyone around you demands an encore? Possibly not, says an ...
Scientists Discover Immunity Mechanism That is Used to Protect the Body from Harmful Bacteria
Scientists have discovered a mechanism that is used to protect the body from harmful bacteria and the findings can provide the science community with ...
Elderly Benefit from Using Implantable Cardioverter Defibrillators
According to new research in the American Heart Association journal Circulation, the elderly may benefit from implantable cardioverter ...
Special Type of IVF May Increase Insulin Resistance Among Offspring
According to a new study from Greece, a special type of in vitro fertilization, or IVF, may increase the risk for insulin resistance among children ...
Weak Brain Connections Found in Autistic Children
Researchers said that some children with autism have weak brain connections in regions that link speech with emotional rewards, possibly signaling a ...
Preventing Death of Immature Ovarian Eggs from Chemotherapy
Young women who are cancer patients, often lose their fertility because chemotherapy and radiation can damage or kill their immature ovarian eggs, ...
- Health News Index
- News Quick Links
 | News Central | | Health Watch | |
| Latest Health News | | Health In Focus | |
| News Category (500+) | | Breaking Health News | |
| Popular News | | Celebrating Life | |
| Health News and Press Release | | Medindia - Exclusive | |
| News Photo Gallery | | India Special | |
| News Video Gallery | | Lifestyle and Wellness | |
| News From Other Resources | |||
 |
Exercise
Complete Medindia Resources
|
| News Categories: |
| » | Research Reveals Early Age Screening Could Aid Breast Cancer Fight |
| » | Blood Tests can be Used to Detect Cancers Caused by Oral Sex |
| » | Exposure to BPA Boosts Risk of Prostate Cancer |
| » | Researchers Use Math to Kill Cancer Cells |
| » | Simple Ways to Prevent Skin Cancer |
| More Cancer News | |
|
Ask an Expert
