Endemic Cholera can Be Contained Through Mass Vaccinations

Category: General Health News
Tuesday, November 27, 2007 at 4:42:18 PM
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A vaccine that is used to prevent travellers from cholera, which characterized by diarrhoea and severe dehydration, may also be used to prevent people living in cholera-prone areas, say researchers.

Published in PLoS Medicine, Ira Longini’s study lends support to the idea that public-health officials should consider mass vaccination in their efforts to control endemic cholera.


The researchers used a mathematical model for cholera transmission, based on information from the Matlab region of Bangladesh, in their study.

They found that cholera outbreaks could be controlled by vaccinating as few as half of the population in an affected region.

According to them, vaccinating only 50 per cent of the population could reduce the number of cholera cases among unvaccinated people by 89 per cent, and among the entire population by 93 per cent.

The researchers said that the incidence of cholera could fall by three-quarters even if only a third of the population was vaccinated.

They reckoned that in areas where there was less natural immunity to cholera, 70 per cent of the population would probably require to be vaccinated to control the disease.

The best way to prevent cholera is to ensure that everyone has access to safe water and good sanitation, but these remain unavailable in many countries, and in situations of population displacement such as refugee camps and disasters such as floods.

Source-ANI
SRM/P
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Medindia on Cholera
Cholera is a severe diarrhoeal disease characterised by sudden onset of effortless vomiting and profuse watery diarrhea. Illness occurring in more than 90% of people is of mild or moderate severity and is difficult to distinguish clinically from other forms of diarrhoeal diseases. Less than 10% of infected persons develop typical cholera with signs of moderate or severe dehydration.

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