Effective TB Vaccine

by Sheela Philomena on  February 21, 2011 at 3:41 PM Respiratory Disease News
RSS Email Print This Page Comment bookmark
Font : A-A+

Researchers have improved the effectiveness of the vaccine for tuberculosis. The work was done by Nele Festjens and Nico Callewaert of VIB and Ghent University.

The new vaccine affords - as already proven in mice - better protection against the disease.
 Effective TB Vaccine
Effective TB Vaccine

"Our vaccine is more effective because it is more quickly recognized by the immune system of the vaccinated person. We have, as it were, undressed the existing vaccine by removing its protective shield," said Nico Callewaert.

The bacterium from which the BCG vaccine is derived hides as it were from the immune system of the organism in which it ends up. This may well be the reason why the vaccine is not very effective. The fact is that a vaccine is meant to trigger an immune reaction in order to be able to afford good protection.

Festjens and Callewaert have discovered that the bacterium hides behind the SapM enzyme that acts as a kind of shield.

They have used this knowledge to develop a new vaccine. They adapted Mycobacterium bovis BCG in such a way that it was no longer able to generate SapM and could therefore no longer hide from the immune system. Testing the new vaccine on mice has shown that it affords better protection than the present BCG vaccine.

Source: ANI

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

This is good news. There is a need for a better TB vaccine and this latest discovery will surely benefit a lot of people and perhaps can reduce the TB disease.

More News on:

Tuberculosis AIDS/HIV Silicosis Screening Tests for Tuberculosis 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...