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Early Interventions for Schizophrenia Lack Evidence
Taken together, however, the studies add up to "a growing body of evidence that there are some special things we can do for people in the early stage of the illness," said Max Marshall, M.D., professor of community psychiatry at University of Manchester in the UK and lead review author.
Early intervention is a critical issue in schizophrenia. "If we could get people at an earlier stage, they would be less ill," and the disease would not yet have wreaked the damage to social, vocational and family life that often accumulates, said Oliver Freudenreich, M.D., director of the First Episode and Early Psychosis Program at Massachusetts General Hospital. He has no affiliation with the review.
"The illness strikes in the developmental years; once someone drops out of school it changes his or her life trajectory the more episodes occur, the harder it is to sustain a job or get a job back," Freudenreich said.
The review appears in the latest issue of The Cochrane Library, a publication of the Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.
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