Adding ultrasound to mammography finds more cancers than mammography alone, but also substantially increases the number of false positives.
At this point, its not clear whether the benefit provided by ultrasound outweighs the additional expense, stress and inconvenience caused by the false positives, said study co-author Etta Pisano, M.D., vice dean for academic affairs in the University of North Carolina at Chapel Hill School of Medicine, Kenan professor of radiology and biomedical engineering and director of the UNC Biomedical Research Imaging Center.
We know that ultrasound does find more cancers. The question is, does it find enough more cancers to make it worthwhile" she said.
The results were presented today (Sept. 28) at the American College of Radiologys fall meeting in Washington, D.C.
The studys principal investigator and lead author is Wendie A. Berg, M.D., Ph.D., of American Radiology Services, located at Johns Hopkins at Greenspring Station in Lutherville, Md. UNC Hospitals is one of the primary study sites, with an enrollment of 198 women (7.5 percent of the study participants).
In the study, 2,637 women at high risk for breast cancer received both mammography and ultrasound exams. The tests were performed by physicians who received special training in breast ultrasound screening. Among the participants, 41 breast cancers were found in 40 women (one had cancer in both breasts) by one or both of the tests. Twelve of the cancers were found by ultrasound alone.