Disease-causing Pathogens in a Region Could be Predicted by Climate and Fauna

A new study says it is possible to predict the number of kinds of disease-causing pathogens in a region just by knowing its climate or the number of birds and mammals found there.

Led by Dr. Rob Dunn at North Carolina State University alongside an international team of biologists and social scientists, the study examined the geography of human disease.

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Dunn said that many factors might influence the diversity of pathogens in a region-human population size and density, the amount of time people have lived there or expenditures on disease control.

Each of these undoubtedly has some influence, but the environment is dominant.

"We imagine that we have nature under control, but nobody seems to have told nature. The environment and, in its broadest sense, nature determines the number of kinds of diseases in different regions of the world in much the way that it has influenced the number of kinds of birds, mammals, ants or bees," said Dunn.

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But while the environment determines how many diseases one finds in a region, it does not determine how common they are.

The researchers also examined the factors correlated to the prevalence, or commonness, of human pathogens across the globe and discovered that the most important factor is health-care spending, specifically expenditures on disease control.

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"On the one hand, we are not very effective at altering the numbers of kinds of pathogens present, as those numbers are strongly correlated with environmental conditions. The vagaries of climate and life over which we have little control determine which diseases you are at risk of contracting in any given place. But on the other hand, we can control the prevalence of pathogens by spending money on disease-control efforts. It is that prevalence that influences human health and well-being," said Dunn.

Climate and geographic variables, population data, disease-control data, pathogen data and human history data were all factored into statistical models that attempted to show which factors had stronger correlations to disease.

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Geographic regions with lots of different kinds of birds and mammals are correlated with the presence of lots of pathogens.

The most likely explanation for this relationship is simply that the same environmental factors have influenced patterns in diversity of human pathogens that have patterns in the diversity of the rest of life, including the birds and mammals.

However, Dunn asserted that reducing bird and mammal diversity will not remove the diseases.

In fact, making wild birds and mammals more rare seems likely to increase the diversity of human diseases, with diseases on rare mammals and birds all too eager to jump from their sinking ships.

The study appears online in Proceedings of the Royal Society of London.

Source-ANI
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