Dermytol(tm), which is a proprietary blend extracted from canola, was able to significantly reduce malignant melanoma cell growth, a new study has indicated.
Dermytol(tm), a proprietary compound developed by KGK Synergize Inc., a biotechnology company in Ontario Canada, is designed to protect skin cells from damage that may lead to skin cancer."Dermytol(tm) has the potential to be used in anti-aging and sun-protection products to reduce damage to skin," Mal Evans, DVM, MSc, PhD, KGK Synergize Inc's Scientific Director, said.
To test the effects of Dermytol(tm), researchers fed male mice with either a Dermytol(tm)-canola oil mixture or just canola oil.
In a separate part of the study, either a Dermytol(tm) cream or a placebo cream was applied onto the shaved skin of a different group of mice.
After seven days of treatment, researchers injected all the mice with malignant melanoma tumour cells.
Dermytol(tm) or placebo treatments continued for 25 days.
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The orally treated mice showed an average decrease in tumour size by about 45 percent as compared to the controls.
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In this study and previous studies, Dermytol(tm) showed no adverse effects.
In a laboratory cell culture study, Dermytol(tm) inhibited the proliferation of human cancer cells.
In a separate study, dietary supplementation with Dermytol(tm) moderately delayed the onset of skin tumours and significantly reduced tumour growth rate in mice treated to induce non-melanoma skin cancers.
A trial including 45 subjects with actinic keratoses - precancerous skin lesions - is underway.
"The current treatment for actinic keratoses is removal by freezing which can be painful or the application of a cream that causes inflammation and blistering of the skin. We expect Dermytol(tm) to be a welcome option," Evans said.
The study was presented at the Experimental Biology Annual Meeting.
Source-ANI
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