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Dementia in Older Adults With Certain Cognitive Deficits may be Predicted by High Blood Pressure
"Although midlife hypertension has been confirmed as a risk factor for the development of dementia in late life, there have been conflicting findings about the role of late-life hypertension," the authors write as background information in the article. Individuals with mild cognitive (thinking, learning and memory) impairment-the state between aging-related brain changes and fully developed dementia-may experience deficits in different domains. For instance, some have impairments only in memory function and are more likely to develop Alzheimer''s disease, whereas those whose impairment follows a stroke or other vascular (blood vessel-related) event often experience executive dysfunction.
"Because hypertension is a major risk factor for vascular brain diseases and vascular cognitive impairment, we postulated that the cognitive domain of dysfunction may be the crucial factor that determines the association between hypertension and cognitive deterioration," the authors write. To test this hypothesis, Shahram Oveisgharan, M.D., of University of Western Ontario, Canada, and Isfahan University of Medical Sciences, Isfahan, Iran, and Vladimir Hachinski, M.D., F.R.C.P.C., D.Sc.(Lond)., also of University of Western Ontario, studied 990 older adults (average age 83) with cognitive impairment but no dementia.
Over a five-year follow-up period, dementia developed at approximately the same rate among participants with and without hypertension (59.5 percent of individuals with high blood pressure vs. 64.2 percent of those without). A similar pattern was observed among those with memory dysfunction alone and with both memory and executive dysfunction. However, among patients with executive dysfunction only, presence of hypertension was associated with an increased risk of developing dementia (57.7 percent of those with high blood pressure progressed to dementia, vs. 28 percent of those without).
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More News on: High Blood Pressure, Alzheimers Disease, Blood Group, Schizophrenia, Blood Group Calculator, Diet Lifestyle and Heart Disease, Diet and High Blood Pressure, Stress and the Gender Divide, Stroke, Quiz on Hypertension
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