A team of scientists in the U.S. have deciphered the highly unusual molecular structure of a natural sea compound, which is shedding new light on the function of mammalian nerve cells.
The team of collaborators from Scripps Institution of Oceanography at the University of California-San Diego (UC San Diego) and Creighton University have found that cyanobacteria, tiny photosynthetic sea organisms, produce a compound with a structure previously unseen in biomedicine.
Novel Therapeutic Target for Parkinson's Disease Identified
Scientists from University of Helsinki Institute of Biotechnology have identified a novel therapeutic target for Parkinson's disease.
Scientists from University of Helsinki Institute of Biotechnology have identified a novel therapeutic target for Parkinson's disease.
"We have seen some of hoiamide A's features in other molecules, but separately. We believe this new template may be important because it's showing different mechanisms of action-different ways to interact with neurons, possibly with a good therapeutic effect for such diseases as epilepsy, hypoxia-ischemia and several neurodegenerative disorders," said Alban Pereira, a postdoctoral researcher in Scripps' CMBB.
The researchers have also revealed that pharmacological tests have shown that Hoiamide A interacts with the same important therapeutic target as analgesic, antiarrhythmic, antiepileptic, and neuroprotective drugs.
Patients With Skin Disease Show Brain Immunity to Faces of Disgust
New research has found that people with psoriasis are less likely to react to looks of disgust by others than people without the condition.
New research has found that people with psoriasis are less likely to react to looks of disgust by others than people without the condition.
"The toxins serve as 'molecular tools' for manipulating cells at an extremely microscopic scale. Ultimately, by understanding how neurons work at this detailed level, and having a set of tools such as hoiamide A, we can envision the development of new, more effective treatments for such diverse conditions as epilepsy, pain control and memory and cognition enhancement.
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Scientists Develop Gene Therapy Method to Prevent Some Inherited Diseases
Researchers have developed one of the first forms of genetic therapy – a therapy aimed at preventing serious diseases in unborn children.
Researchers have developed one of the first forms of genetic therapy – a therapy aimed at preventing serious diseases in unborn children.
A research article describing the study has been published in the journal Chemistry and Biology.
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Feeling Hopeless May Put Women At Greater Risk For Heart Disease And Stroke
Universities of Minnesota Medical School scientists say that the feeling of hopelessness may make increase the risk of stroke in women.
Universities of Minnesota Medical School scientists say that the feeling of hopelessness may make increase the risk of stroke in women.
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