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Decaf Coffee, Nicotine-free Tobacco Linked to Parkinson's Prevention
Leo Pallanck, a neuroscientist at the University of Washington in Seattle, whose team led the new study, said that if they could identify the compounds that put up this brain defence, they could offer a preventive Parkinson's treatment where none currently exists.
"We think that there's something else in coffee and tobacco that's really important," New Scientist quoted him as saying.
Epidemiological studies have suggested that coffee-drinkers and smokers are less likely to develop Parkinson's than abstainers.
"A lot of the field has gravitated to the idea that it's caffeine and nicotine [that protects their brains]," said Pallanck.
To see if ingredients other than caffeine and nicotine might be providing the benefit, Pallanck's team turned to fruit flies with a condition similar to Parkinson's disease.
The flies have mutations that kill off dopamine-producing neurons, which causes them to develop movement and cognitive problems like those characteristic of Parkinson's in people.
The same mutations are linked to hereditary forms of Parkinson's in humans.
The researchers prepared several fly foods spiced up with normal coffee, decaffeinated coffee, smokeless "dipping" tobacco designed to allow nicotine absorption via the mouth, or a commercial nicotine-free tobacco.
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