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Dad's Weight Plays Crucial Role in IVF Success: Study

by VR Sreeraman on  November 1, 2010 at 3:37 PM Obesity News   - G J E 4
The chances of success in assisted reproductive technology drops if the father is overweight, according to a new study.

Experts have revealed that for couples using IVF, an overweight dad may lower the chances of pregnancy, reports ABC News.
 Dad's Weight Plays Crucial Role in IVF Success: Study
Dad's Weight Plays Crucial Role in IVF Success: Study
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According to the study, conducted by Dr Zaher Merhi of Albert Einstein College of Medicine and Montefiore Medical Center in New York City, for every increase of 5 units in the father's BMI, the couple's chances of getting pregnant decrease by a whopping 28 percent.

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As there were no differences in the quality or concentration of sperm or day-three embryo quality between couples with an overweight male partner and those with a normal-weight male, some unknown factor must explain the association, Merhi said at the American Society for Reproductive Medicine here.

He said his group plans on evaluating the quality of the day-five embryos to see whether there is a difference there.

The relationship also may involve a factor that cannot be seen at the embryo stage with a microscope, perhaps an increase in sperm DNA fragmentation, which has been demonstrated previously in obese men, he said.

If further research confirms the findings of the current study, clinicians may need to start counseling men as well as women about losing weight before undergoing in vitro fertilization, rather than focusing on female BMI, said Merhi.

To evaluate the association between an overweight male partner and the success of assisted reproductive technology, Merhi and his colleagues analyzed data from cycles performed at their center from 2007 to 2008.

The analysis was limited to 251 fresh in vitro fertilization/intracytoplasmic sperm injection embryo transfer cycles using a woman's own oocytes and her partner's sperm.

Overall, 37.5 percent of the cycles resulted in clinical pregnancy, with a lower rate in couples with an overweight male partner (BMI of at least 25) compared with those with a normal-weight man.

Couples with an overweight male also had a higher female BMI and more embryos transferred.

Sperm concentration, the total number of motile sperm, and the percentage of men with low sperm count were similar in couples with an overweight male and those with a normal-weight male.

Source: ANI
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