Customised HIV Treatment Closer to Reality

by Rajshri on  November 28, 2009 at 8:43 PM AIDS/HIV News
RSS Email Print This Page Comment
 Customised HIV Treatment Closer to Reality
An innovative, customized HIV treatment that has proved to be more effective against the virus than the anti-retroviral cocktails currently used has been developed by scientists from McGill University.
Advertisement

The new therapy developed by Dr. J-P. Routy of McGill University and Dr. R. Sékaly from the Université de Montréal has successfully passed its first clinical trial.

Advertisement
It uses dendritic cells, which are removed from each HIV-infected patient and subsequently multiplied in-vitro.

"This is a vaccine made for the individual patient - an "haute couture" therapy, instead of an off-the-rack treatment," said Dr Routy.

Dendritic cells present material from invading viruses on their surface, allowing the rest of the immune system to identify and attack the invaders.

"They are the "grand conductors" of the immune response. With them, you push the immune system, in all its functions, at the same time," said Routy.

In the current trial, dendritic cells were exposed to a sample of HIV RNA (ribonucleic acid) specific to the patient involved. This exposure encouraged the cells to develop defences specific to that viral strain

The modified cells - called AGS-004 - were then injected back into the patients.

The researchers also measured increased levels of CD8-lymphocytes in the patients - the "attack" cells of the human immune system that the treatment is intended to mobilize, thus confirming that the intervention was targeted and controlled.

The results were published recently in Clinical Immunology.

Source: ANI
RAS
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Oral Health And AIDS AIDS/HIV AIDS/HIV - Epidemiology AIDS/HIV - Clinical Features AIDS/HIV - Health Education AIDS/HIV - Prevention And Transmission AIDS / HIV - Treatment AIDS/HIV- Lab Tests and Faqs Prostitution: Fresh Stakes in the Oldest Trade HIV Symptom 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive