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Common Skin Creams can Cause Skin Cancer: Study

by Sreeraman on August 15, 2008 at 9:27 AM Cancer News

Moisturisers used by millions of people induced skin cancer in experiments on mice, a study released Thursday said, as experts expressed strong doubts over any possible risk to humans from creams.

Common Skin Creams can Cause Skin Cancer: Study

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Researchers at Rutgers University, New Jersey, in the United States tested four common skin creams on gene-altered hairless mice exposed to heavy doses of cancer-causing UV light.

The scientist who led the study, however, cautioned that rodent skin is more sensitive than human skin, while other experts said they had reservations about the relevance of the study's conclusions.

Rates of non-melanoma skin cancers increased between 24 and 95 percent compared to control mice not treated with creams, the study found.

Non-melanoma skin cancer is very common in humans, and is curable surgically. In very rare cases, however, it can prove fatal.

When the scientists, led by Allan Conney, repeated the experiments with a made-to-order cream missing several suspect ingredients -- including mineral oil and sodium lauryl sulfate -- the cancer rates dropped sharply.

Conney said that further studies were needed to test the impact of topical creams on people as rodent skin, usually covered by fur, is thinner and more permeable than human skin.

His findings were published in the Journal of Investigative Dermatology, part of the Nature Publishing Group in Britain.

Experts familiar with the study doubted its significance for humans.

"The UV source used to pre-sensitise the mice is a very poor surrogate for sun exposure," commented Brian Diffey, an emeritus professor at Newcastle University in Britain.

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