A harmless virus, which is encountered by most infants and displays few symptoms, may trigger type 1 diabetes, according to a new study.
Researchers at the Norwegian Institute of Public Health, who conducted the study, suggested that this "silent" Human parechovirus should be taken into consideration when looking for triggers for type 1 diabetes among those who are genetically at risk.
This study was conducted as part of a long-term project to examine if environmental risk factors affect type 1 diabetes.
For closer study, faecal samples and questionnaires about the health of 102 children were sent in monthly by their parents. Researchers wanted to see how common human parechovirus infections were among Norwegian infants.
Existing research indicates that a related virus, which only affects rodents, Ljungan virus, has been linked to the development of rodent diabetes.
By studying stool samples from 102 infants and comparing feedback from parents about their child's health over three years, no significant link could be found between infection episodes and typical symptoms such as coughing, sneezing, vomiting, diarrhoea or fever.
By the age of two, 86 percent of the infants had evidence of parechovirus in their faeces, and 94 percent by the age of three. Human parechovirus 1 was the most prevalent type (76 percent) followed by human parechoviruses 3 and 6 (13 percent and 9 percent respectively).
The researchers also found an increase in parechovirus infection between the ages of 6 and 18 months.